How common is anaphylaxis with immunotherapy? Anaphylaxis is a life-threatening allergy reaction that happens when you start to have trouble breathing, or you feel like you're going to pass out, or you have wheezing.
Thankfully, it's pretty rare with immunotherapy. Now, for allergy shots, the risk of anaphylaxis is thought to be one in 25 million injections. So it's pretty rare.
With sublingual immunotherapy, or oral immunotherapy, it's thought to be one in a hundred million, so incredibly rare. And this is why we let you do it at home. Thankfully, no one has ever died from sublingual immunotherapy to date.
Ultimately, you should work with your physician to pick the best type of immunotherapy for you and your allergies.